Thanks Michael,
We have done the same from Monday 4th January 2016, but one of the GP leads has pointed to this novel use of GGT.
Mohammad
Dr. M A Al-Jubouri, MB ChB, MSc, EurClinChem, FRCP Edin, FRCPath
Consultant Chemical Pathologist
--------------------------------------------
On Wed, 6/1/16, Colley, Michael <[log in to unmask]> wrote:
Subject: Re: Gamma GT & all casue mortality
To: [log in to unmask]
Date: Wednesday, 6 January, 2016, 14:24
At the request of our Hepatologists /
gastroenterologists we have, starting today, removed GGT
from our LFT panel.
We await the result.
Michael
-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]]
On Behalf Of Mohammad Al-Jubouri
Sent: 06 January 2016 14:21
To: [log in to unmask]
Subject: Gamma GT & all casue mortality
Dear List members,
High GGT even at upper reference limit has been reported to
be associated with risk of increased all cause mortality as
well as cardiovascular, type 2 diabetes and cancer
mortality, see this meta-analysis:
http://www.tandfonline.com/doi/full/10.3109/10715762.2014.902055
Is there enough evidence to justify its routine measurement
as part of routine LFT profile? And if elevated what
intervention the clinician could instigate to reduce risk of
mortality?
I am not a fan of GGT because of its high sensitivity and
low specificity but would welcome a debate on this novel use
of GGT.
Best regards
Mohammad
Dr. M A Al-Jubouri, MB ChB, MSc, EurClinChem, FRCP Edin,
FRCPath Consultant Chemical Pathologist
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