At the request of our Hepatologists / gastroenterologists we have, starting today, removed GGT from our LFT panel.
We await the result.
Michael
-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Mohammad Al-Jubouri
Sent: 06 January 2016 14:21
To: [log in to unmask]
Subject: Gamma GT & all casue mortality
Dear List members,
High GGT even at upper reference limit has been reported to be associated with risk of increased all cause mortality as well as cardiovascular, type 2 diabetes and cancer mortality, see this meta-analysis:
http://www.tandfonline.com/doi/full/10.3109/10715762.2014.902055
Is there enough evidence to justify its routine measurement as part of routine LFT profile? And if elevated what intervention the clinician could instigate to reduce risk of mortality?
I am not a fan of GGT because of its high sensitivity and low specificity but would welcome a debate on this novel use of GGT.
Best regards
Mohammad
Dr. M A Al-Jubouri, MB ChB, MSc, EurClinChem, FRCP Edin, FRCPath Consultant Chemical Pathologist
------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry.
Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
Green Laboratories Work
http://www.laboratorymedicine.nhs.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
Great Western Hospitals NHS Foundation Trust Great Western Hospital Marlborough Road Swindon
SN3 6BB
Tel 01793 60 40 20
http://www.gwh.nhs.uk
Register to become a member of the Trust at https://members.gwh.nhs.uk
This message and any files transmitted with it are confidential and intended solely for the individual(s) addressed.
If you believe you have received this e-mail in error, disclosing, copying, distributing or retaining this message, or any part of it, is strictly prohibited; please notify the sender immediately and delete it from your system.
Any views or opinions presented are solely those of the author and do not necessarily represent those of Great Western Hospitals NHS Foundation Trust.
All messages sent by the Trust are checked for viruses but this does not, and cannot, guarantee that a virus has not been transmitted.
The Trust accepts no liability for any damage caused by any virus transmitted with this e-mail.
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical community working in clinical biochemistry.
Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
Green Laboratories Work
http://www.laboratorymedicine.nhs.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
|