The fact that they state that the "turbo"PTH assay is not affected makes it
even more confusing. Both assays are basically the same, except for the
exact concentrations of the contents. Aren't they?
Bart Ballieux
Dr.Ir. B.E.P.B. Ballieux
Klinisch Chemicus
CKCL, E2-P
Leids Universitair Medisch Centrum
Postbus 9600
2300 RC Leiden
Tel: 071-5262165/2278
Fax: 071-5266753
email: [log in to unmask]
-----Original Message-----
From: [log in to unmask] [mailto:[log in to unmask]]
Sent: donderdag 18 maart 2004 13:36
To: [log in to unmask]
Subject: Re DPC withdrawing EDTA sample as suitable for DPC Immulite
2000
DPC are issuing a letter saying they no longer consider EDTA as a suitable
sample for PTH on the Immulite 2000. The reason is that it caused a positive
shift of 30% with some users with a certain lot Number 117 and 118. So it
appears that they fear an interference with their method, and the answer
appears to be to go back to serum. However, my understanding of the
literature is that EDTA sample is a truer reflection of the PTH level, in
that PTH is more stgable in EDTA than serum. The data on the letter does not
address the issue of which sample type gives a more accurate reflection of
the PTH level, and appears not to have strong supportive evidence for the
change.
What sample types are others using, and are DPC users going to revert to
serum?
____________________________________________________________
Dr. Helen Grimes, Dept. of Clinical Biochemistry, UCH, Galway, Ireland
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