I think this discussion is getting silly
We are dealing with minutiae here. We old 'uns remember when a GTT was 50 g
glucose and we now use 75 g glucose. Has anyone sat down and worked out the
difference that the 419 to 394 mL makes. (there's a challenge to someone
with the time !)
I would conjecture that the average GTT operative would be hard pressed to
give the right volume anyway, considering GSK sell several different volume
bottles all around the 200-400 mL volumes.
Perhaps we ought to check the hydration stat of the patient before we start
(how many cups of tea did you say Mrs Jones ?) and adjust the "250-300" to
match the result.
Let's get real and think physiology. There are some things which are
achievable in terms of precision and it is acknowledged that we chase
impossible dreams in NEQAS without getting paranoid about volumes of drink
!! Don't tell CPA or they will want to accredit the drinking vessels in
out-patients as well!
Happy holidays
With best wishes
Richard
-----Original Message-----
From: Hyde Philip (ULHT) [mailto:[log in to unmask]]
Sent: Friday, May 03, 2002 10:26
To: [log in to unmask]
Subject: Re: Lucozade and GTT changed formulation
Apologies for my potential ignorance in this matter, but is "250-300" ml an
evidence-based volume or an approximation based on anecdote ?
Philip Hyde,
Pilgrim Hospital
Boston
UK
-----Original Message-----
From: Stephen Davis [mailto:[log in to unmask]]
Sent: 03 May 2002 08:46
To: [log in to unmask]
Subject: Re: Lucozade and GTT changed formulation
The WHO guidelines for the performance of the oral glucose tolerance test
requires the glucose load to be given in a volume of 250 - 300 mL. To give
the equivalent of 75 g anhydrous glucose using Lucozade requires a volume of
394 mL. GSK quote the 1999 WHO Report "Definition, Diagnosis and
Classification of Diabetes Mellitus and its Complications" in their flyer
but fail to mention Lucozade's shortcomings for the test!
Steve Davis
Principal Biochemist
Department of Clinical Biochemistry
Royal Glamorgan Hospital
Ynysmaerdy
PONTYCLUN
CF72 8XR
Tel : +44 (0)1443 443357
Fax: +44 (0)1443 443355
> -----Original Message-----
> From: Gray Malcolm [SMTP:[log in to unmask]]
> Sent: Thursday, May 02, 2002 3:14 PM
> To: [log in to unmask]
> Subject: Re: Lucozade and GTT changed formulation
>
> Here is the flier from GSK relating to the change to the Lucozade
> formulation, for any colleagues who were not aware of the change.
>
> In Word format: <<gttsheet02.doc>>
>
> In Acrobat <<gttsheet02.pdf>>
>
> When I checked up on the change, I asked the Nutrition department at GSK
> to
> make sure that adverts for these changes are published in the ACB news
> sheet, so that those concerned with the testing wouldn't have to hear from
> GP colleagues etc. Haven't seen anything yet, but you never know.
>
> Malcolm Gray
> Clinical Biochemistry
> St. Bartholomew's Hospital
> West Smithfield
> LONDON EC1A 7BE
> Tel: 020 7601 8253
> Mobile 0794 100 7290
>
>
> --------------------------------------------------------------------------
> The information contained in this message is confidential and is intended
> for the addressee only. If you have received this message in error or
> there
> are any problems please notify the originator immediately. The
> unauthorised
> use, disclosure, copying or alteration of this message is strictly
> forbidden. This mail and any attachments have been scanned for viruses
> prior
> to leaving Barts & The London NHS Trust network. Barts & The London NHS
> Trust will not be liable for direct, special, indirect or consequential
> damages arising from alteration of the contents of this message by
> a third party or as a result of any virus being passed on.
> --------------------------------------------------------------------------
>
> << File: gttsheet02.doc >> << File: gttsheet02.pdf >>
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical
community working in clinical biochemistry.
Please note, archived messages are public and can be viewed
via the internet. Views expressed are those of the individual and
they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical
community working in clinical biochemistry.
Please note, archived messages are public and can be viewed
via the internet. Views expressed are those of the individual and
they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical
community working in clinical biochemistry.
Please note, archived messages are public and can be viewed
via the internet. Views expressed are those of the individual and
they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
|