The nephrologists Stewart Cameron and Rainer Greger in their chapter on
renal function testing in the Oxford Textbook of Clinical Nephrology (1998;
1.3: 39-69) wrote that for ordinary clinical purposes, when serum creatinine
is over 200 umol/L it alone is adequate for assessing glomerular function,
but below that value an isotopic method for measuring GFR should be used
rather than creatinine clearance. Your near anuric patient almost certainly
has a serum creatinine over 200 umol/L and I think that attempting to
measure creatinine clearance wiould be a waste of resources..
Brian Payne
Michael Steiner wrote:
> We have a request for a creatinine clearance based on a 24h urine output
> of only 120 ml (near anuric patient). I am in doubt if the analysis of
> clearance will yield clinically useful information given the low urine
> volume.
> I would like to learn if other labs reject creatinine clearance requests
> provided the 24 h urine volume is below a certain limit.
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