Dear Colleagues,
We have repeatedly been asked to do creatinine clearance in patients
with an urinary output of about 200 ml/24h (our collection period).
An appropriate urine flow rate seems to be a prerequisite for the
meaningful analysis of creatinine clearance. Therefore, I ask you to
comment on the usefulness of this test in the above mentioned patients.
Should we set a lower limit for the urine volume produced in 24 hours?
Obviously, creatinine clearance would be useless in minimal urine
output.
Thank you very much for your input.
Sincerely,
Dr. med. Michael Steiner
University of Rostock
Institute of Clinical Chemistry and Pathobiochemistry
Ernst-Heydemann-Str. 6
D-18057 Rostock
GERMANY
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