Dear All



I am hoping that the collective brain can help. 

We have had a positive xanthochromia scan, we (our software) performed a correction as there was no distinct oxyhaemoglobin peak. I appreciate that this is normal practice as per the guidelines but the patient's serum bilirubin concentration was 350umol/l   (CSF protein 0.46g/l and serum total protein 58g/l).



Is anyone aware of any evidence regarding the range of serum bilirubin that the adjustment equation is valid for?

Is there a serum bilirubin concentration above which you could not reliably detect a SAH by spectrophotometric methods?



I am trying to ascertain if the correction / measurement is valid in this patient. 



Any help gratefully received.

Paula





Dr Paula Marchetti PhD FRCPath

Consultant Clinical Scientist

Department of Clinical Biochemistry 

The Rotherham NHS Foundation Trust 

Moorgate Road

Rotherham

S60 2UD



t: 01709 42 4103

Secretary: Claire Hawley 01709 42 4051

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