How about an “n of 1 trial”?
Jonathan
On 10 Sep 2014, at 08:23, Reynolds Tim (RJF) BHFT <[log in to unmask]> wrote:
> I have had a lot of meetings with her and am convinced she is taking the tablets. Also, the symptomatic improvement from the T3 is remarkable. On reflection, I think I will have to try to get the histology results and possibly the notes from the hospital that did the op. It would be interesting to know what symptoms were / lab results before she had the thyroidectomy.
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> Whilst there are some patients who are mad there are some that really do seem to need T3. I have one patient (age
> 22) whose TSH remains
> 100. On doses of up to 500mg of T4 there was no change but when given T3, she lost weight and began to resume normal activities [she can even make it to clinic on time now instead of turning up 3 hours late]. Even now on T3 her TSH has not dropped much but the obviously symptomatic hypothyroidism has resolved and she is much better. Biochemistry does not always give the right answers...
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