Dear Clemens,
For the choice of derivatization compounds this might be helpfull:
Z. Dauter (2005). C. R. Chimie 8, 1808-1814.
Best Regards,
Georg
Clemens Grimm wrote:
> Dear all,
>
> after the SeMet phasing discussion, what would be -in general- the
> best technique to phase low resolution data (<=4A) of large complexes
> (>=150 kDA) - in terms of
>
> - derivatization compounds (is there something like the 'golden five'
> HA compounds for these cases),
>
> - data collection techniques and
>
> - phasing methods?
>
> Clemens
--
Universität Tübingen
Interfakultäres Institut für Biochemie
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