Dear all,
Like Mike, we also don't comment on low ALP (unless it's a paediatric
case). Low ALP, <50 iu/L is relatively common, most cases attributed to
drugs such as methotrexate and azathiaprine. We have also seen low
levels with hypothyroidism. Metal co-factor (magnesium and zinc)
deficiency is also a possibility, though we haven't seen any cases in
our lab.
Regards,
Rafaq Azad.
>>> "PD Dr. Michael Steiner" <[log in to unmask]>
16/03/2009 14:22 >>>
Dear colleagues,
A lower limit of normal should be provided and adjusted for age
(groups).
We usually do not add comments. The story of low AP being typical of
Wilson's disease has been with the clinical community for decades.
However, at least one study refused that claim.
Hereditary hypophosphatasia (rare!) may be another suggestion.
Best regards
Mike
****************************************
PD Dr. med. Michael Steiner
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Tel: +49-381-7022701
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Medizinisches Labor Rostock
Südring 81, D-18059 Rostock
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