Dear colleagues,
A GP asks about the differential diagnosis of increased GGT in a 20 year
old young lady. She is perfectly fine except for slightly elevated GGT
(appr 2.5 upper limit) which has been persisting for a couple of months.
Transaminases, bilirubin, alkaline phosphatase, and LDH are normal. No
evidence of drugs, alcohol, and current therapy of any kind including
hormonal contraception.
One suggestion was early-stage primary biliary cirrhosis (or similar). Any
comments on that one?
What I am confused most about is that the increase concerns ONLY and
EXCEPTIONALLY GGT. Any idea if a macro-GGT has ever been described? If so,
any advice how rule in/out a macro-GGT?
Your suggestions will be much appreciated.
Best regards,
Mike
Dr Michael Steiner
Medizinisches Labor Rostock
Suedring 81
D-18059 Rostock
GERMANY
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