If the question relates to patients who have already reached target, say 20 mcg/l and are being monitored to keep ferrtin to the magic target of 50 then % sat needs to be checked every time. It is not always easy to keep %sat under control when ferritin is <50 because you may make patient anaemic. In he early stages venesection there it little point in checking %sat and ferritin only should suffice. For long term monitoring it is important to measure CRP with ferritin so that patients with intercurrent illnesses don’t get venesected and I have seen happening many times!
rgds
A
Ahmed Waise,
Consultant Chemical Pathologist
Laboratory Medicine,
York Hospitals Foundation Trust,
YORK, North Yorkshire YO31 8HE, UK
[log in to unmask]
01904725855
---- Original message ----
>Date: Wed, 2 Apr 2008 12:51:39 +0100
>From: "COLLINS MICHAEL (RM1) Norfolk and Norwich University Hospital" <[log in to unmask]>
>Subject: Re: Monitoring haemochromatosis treatment
>To: [log in to unmask]
>
> Most of our requests for iron and transferrin
> saturation come from the renal unit where
> transferrin saturation is required for EPO treatment
> guidelines. Because of this we measure iron and
> transferrin and calculate Tsat on every iron
> request.
>
>
> Mike Collins
> BMS3
> Clinical Biochemistry & Haematology
> Norfolk & Norwich Hospital
> Colney Lane Norwich NR4 7UY
>
> -----Original Message-----
> From: Clinical biochemistry discussion list
> [mailto:[log in to unmask]]On Behalf
> Of Roy Fisher
> Sent: 02 April 2008 12:41
> To: [log in to unmask]
> Subject: Monitoring haemochromatosis treatment
>
> Dear All,
> I would appreciate knowing what tests other
> laboratories do for assessing patients having
> regular venesection as treatment for
> haemochromatosis. Ferritin is a well established
> marker for iron stores for which there are target
> values to aim for. However, our
> gastroenterologists also ask for iron transferrin
> saturation as well and get annoyed when we
> occasionally miss doing them. This is usually due
> to lack of clinical details and because we
> don't do these tests to assess anaemia. Do other
> laboratories see this pattern of requesting in
> monitoring these patients and does iron
> transferrin saturation provide additional
> information beyond the initial assessment of iron
> overload?
>
> Many thanks
>
> Roy Fisher
>
>
>
> Dr R A Fisher
> Consultant Biochemist
> Royal Cornwall Hospital
> Tel 01872 252546
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