> I am trying to perform Mouse brain extraction and then
> segmentation on T2 weighted 256 x 256 x 15 16 bit images but not able to
> find the corresponding resources. Can anyone please guide me to achieve
> my aim?
In order for a segmentation algorithm to work, it needs some idea of what the
tissues are that you hope to identify. Sometimes, the approach involves
"supervised learning", whereby a few voxels are labled as being of various
tissue classes. The algorithm then tries to determine a strategy to predict
these lables from information in the images.
The strategy in SPM is kind of semi-supervised, whereby maps that reflect the
probability of different classes are used. The tools in SPM are unlikely to
work unless you can track down tissue probability maps for mouse brains.
There may be other segmentation algorithms out there that do not need tissue
probability maps. Here are a few places to look:
http://idoimaging.com/index.shtml
http://www.cma.mgh.harvard.edu/iatr/
http://www.nitrc.org/
Best regards,
-John
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