When we were using Vitros instruments with a top CRP of 90 we had a
short period when the software controlling our track was giving problems
with dilutions. We reported high CRPs as >90 but received complaints
from some clinicians who were using CRP to follow their patients'
progress.
At the moment using Abbott Architects we report high CRPs as >320 (the
top of the assay range)
Mike Collins
Chief Biomedical Scientist
Automated Lab, Clinical Biochemistry
Norfolk & Norwich University Hospital
Norfolk
England
-----Original Message-----
From: Clinical biochemistry discussion list
[mailto:[log in to unmask]] On Behalf Of Hallworth Mike
(RLZ)
Sent: Friday, May 25, 2007 12:07 PM
To: [log in to unmask]
Subject: CRP - upper limit of reporting
I know we are more often focussing our attention on the lower end of the
CRP spectrum, but can I ask about people's policy on the upper reporting
limit?
We have recently changed from a CRP method with an upper limit of 220
mg/L to one with a much narrower dynamic range and an upper limit of 90
mg/L. In the past, we have always diluted over-range specimens to give a
quantitative result, but are now finding this policy is producing a
crippling burden of dilutions. Do other labs dilute over-range CRPs? At
what level do you report a ">XXX" result? If it's over 90, does it
really matter how high it is?
Emails with your current practice (or, even better, evidence...) would
be much appreciated. I will summarize the response for the mailbase.
Mike
------ACB discussion List Information-------- This is an open discussion
list for the academic and clinical community working in clinical
biochemistry. Please note, archived messages are public and can be
viewed via the internet. Views expressed are those of the individual and
they are responsible for all message content. ACB Web Site
http://www.acb.org.uk List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions
(How to leave etc.) http://www.jiscmail.ac.uk/
This email and any files transmitted with it are confidential and intended solely for the use of the individual or entity to whom
they are addressed.
If you have received this email in error please notify the originator of the message. This footer also confirms that this
email message has been scanned for the presence of computer viruses but this should not be relied upon as a guarantee that the contents are virus free.
Any views expressed in this message are those of the individual sender, except where the sender specifies and with authority,
states them to be the views of the Norfolk and Norwich University Hospital NHS Trust. The information contained in this e-mail may be subject to public disclosure
under the Freedom of Information Act 2000. Unless the information is legally exempt from disclosure, the confidentiality of this e-mail and your reply cannot be guaranteed
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical
community working in clinical biochemistry.
Please note, archived messages are public and can be viewed
via the internet. Views expressed are those of the individual and
they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
|