REMINDER
KEELE UNIVERSITY
CENTRE FOR MEDICAL STATISTICS
SEMINAR SERIES on BIOSTATISTICS 2002/2003
NO 5: Wednesday, February 5th 2003, at 2:30 pm
"Modelling covariance in longitudinal studies"
Professor Gilbert MacKenzie
Keele University
The idea that in longitudinal data analysis (LDA) the mean might be
modelled as a function of time and baseline covariates (eg , the
treatment indicator in an RCT) is well-established. The idea that the
second parameter in the model, the covariance, might be modelled is also
well-establised, but that it might be modelled in a regression.
similarly to the mean is rather new. A third idea, that selection of
the optimal pair of parameters should be "joint", renders much current
practice redundant. We review the key concepts behind joint
mean-covariance modelling in LDA, when the response is continuous,
develop an augmented regression model for the mean and covariance and
present a new algorithm for finding the optimal model in the joint
mean-covariance model space.
Venue: Room 2.22, Third Floor, MacKay Building, Keele University - All
welcome!!
http://www.keele.ac.uk/cwis.html
http://www.keele.ac.uk/depts/ma/news/#medstats
http://www.keele.ac.uk/university/campus/cgm.pdf
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Janet Drewery
Centre for Medical Statistics
Mathematics Department
MacKay Building
Keele University
Keele, Staffs ST5 5BG
Tel: (01782) 583269
Fax: (01782) 584268
E-mail: [log in to unmask]
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