Expires After: 2/6/2003 00:00
I agree these look perculiar, but the info from TSH would suggest a biological
effect, so how is the patient clinically?
Does this suggest that maybe measuring Free T4 on patients given T4 is not of
any great benefit, as in essence all this has done is subjected the patient to
a lot more needles being stuck in him, and if there was good clinical
improvement, was this justified?
(Sorry last comment made with LREC hat on, just having read all this month's
submissions, with lots of unnecessary tests suggested)
-- Never take a no from someone not empowered to give you a yes --
Gary Mascall
Consultant in Clinical Biochemistry
Clinical Biochemistry Department
Kidderminster Hospital
Worcestershire Acute Hospitals NHS Trust
Bewdley Road
Kidderminster, Worcs, UK
DY11 6RJ
Tel : 01562 823424 extn 3465
Fax : 01562 513030
email : [log in to unmask]
>>> Jeff Slater 29/01/03 18:46:28 >>>
Dear all,
Has anyone any explanations for these results:
DPC Immulite 2000
Date Free T4 TSH
15/10/02 8.4 50.9
Patient put on 50 ug T4
30/10/02 8.8 35.2
25/11/02 <2.6 2.59
17/12/02 <2.6 4.43
(Cortisol 193 nmol/L Testosterone 8.7 nmol/L)
27/1/03 Heparin <2.6 9.0
Serum <2.6 8.6 LH 2.5 FSH 2.1
EDTA <2.6 6.32
Bayer Centaur - measured by colleagues elsewhere.
17/12/02 10.3 30.36 Prolactin 171
27/1/03 Heparin 10.3 36.74 Prolactin 169
Serum 10.1 35.87
Patient is male, dob 3/2/33. He has Parkinson's, Coeliac disease ,
Essential hypertension, Pernicious anaemia. He has been prescribed
propanolol,citalopram, thyroxine, and B12 injections 3 monthly. He has
recently started taking glucosamine as an over-the-counter prepn.
On the 27th we bled the chap in the department. Prelim expts had
suggested that EDTA may slightly lower Immulite results and we wondered
if the samples in November/December had been decanted by the surgery
from EDTA samples into heparin tubes. However the effect was
insufficient to account for these discrepancies and this was proved on
the last set of samples.
What can explain these method-dependent differences ?
A very puzzled Jeff Slater
--
Jeff Slater
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------ACB discussion List Information--------
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