Dear Mike,
Greetings from windy (surprisingly sunny!) Suffolk. I may not be the right
person to discuss this issue, as I am neither a health economist nor a
trialist, but I would like to share what I found on this topic.
This discussion on issues in the analysis of cost data from randomised
controlled trials states “If there are separate analysis plans for clinical
and economic evaluations efforts should be made to make them as consistent
as possible for example shared use of an intention to treat analysis” The
discussion is available on line @
http://www.uphs.upenn.edu/dgimhsr/COSTDAT9.PDF
I also found a paper in which the authors have used ITT for both clinical
and economic analysis. The paper can be found @
http://www.acpjc.org/Content/130/1/ISSUE/ACPJC-1999-130-1-004.htm
General issues related to economic evaluation in RCTs is available @
http://www.uphs.upenn.edu/dgimhsr/CTLEC402.PDF
Hope this is of some interest/?help.
I am sure the pundits in health economics will have the final say in the
matter!
Cheers & regards and wishing you a wondeful weekend.
Badri
Dr.P.Badrinath M.D,M.Phil,(Epid)PhD(Cantab)DFPHM(UK),MPH(Distinc)
Specialist Registrar in PHM & Honorary Clinical Lecturer,
Suffolk Public Health Network & University of Cambridge,
PO Box 170, St.Clement's Hospital,
Ipswich IP1 4LA, UK.
Tel: 00 44 1473 329 584
Fax: 00 44 1473 329 090
http://myprofile.cos.com/badrishanthi
"For an excellent review of the current medical literature, go to Journals
Scan www.uaeu.ac.ae/jscan/" - BMJ 3rd June 2000, Netlines
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