Sorry I did not include the year in my previous message.
This particular reference is in one of the last few issues
of Scand J Clin Lab Med of 1999. Sorry for the omission.
Regards
Vivek
London
On Mon, 26 Feb 2001 12:19:54 +0000 (GMT Standard Time)
Vivekanandan Sachidanandam <[log in to unmask]> wrote:
>
> Yes.It is published in one of the last few issues of the
> Scand J Clin Lab Med as a review issue on Laboratory
> Performance. The clinical significance based on biology
> (European) and total error(American) has been given for
> various analytes.
> Regards
> Vivek
> On Sun, 25 Feb 2001 15:58:24 +0100 "Breimer, Lars
> {PDC2~Welwyn}" <[log in to unmask]> wrote:
>
> > Dear Colleagues
> >
> > We all (should) know about analytical and biological variation and their coefficients of variation. And we all have a good idea of what is significant for a patient when we see them in clinic.
> >
> > Please can someone direct me to a simple summary publication / table / website which gives an idiot's guide to how much the value of analyte must have changed to be a clinically signficant change.
> >
> > Perhaps such a table does not exist? However, I seem to remember seeing such information. Perhaps it is not reliable or even downright faulty.
> >
> > Much obliged.
> >
> >
> > Yours sincerely
> >
> >
> >
> > Lars Breimer
> > MA PhD BM BCh MRCPath Dip Pharm Med
> > Clinical Science
> > Global Drug Development
> > Roche Products Limited
> > 40 Broadwater Road
> > Welwyn Garden City
> > Herts
> > AL7 3AY
> > U K
> > Registration Number 100674
>
> ----------------------
> Vivekanandan Sachidanandam
>
>
>
----------------------
Vivekanandan Sachidanandam
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