In message <[log in to unmask]>, Jonathan
Kay <[log in to unmask]> writes
>A neurologist has asked me:
>
>
>> We use a lot of azathioprine. Every now and again we have a disaster
>> or near-disaster with marrow suppression. Should we routinely check
>> thiopurine methyltransferase activity before initiating therapy? I
>> believe the assay is avaiable from the purine lab at Guy's. Should we
>> be doing it locally? What is the cost? Are there any particular
>> technical difficulties?
>>
>
>I would very much appreciate the accumulated wisdom of the list
>members...
>
>
>Jonathan
>
No
They should monitor FBC instead
--
paul collinson
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