Anybody out there (apart from us) still measuring aldolase?
Our local Rheumatology consultants believe that aldolase is of unique value in
the detection and monitoring of certain myopathies, particularly polymyositis
and dermatomyositis, and is often markedly elevated when CK is normal of
minimally increased. Athough we have had samples from a number of patients who
appear to bear this out, we are concerned that aldolase is non-specific and may
be elevated for other reasons, e.g. due to liver involvement in multisystem
disease.
We currently provide the assay, to keep our Rheumatologists happy. Do
Rheumatologists elsewhere feel the same or is this purely a local aberration?
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Home Address:
Dermot Neely
52 Albert St
Durham
DH1 4RJ Tel. 0191-384 6125
Work Address:
Dr R.D.G.Neely
Department of Clinical Biochemistry
Dryburn Hospital
North Road
Durham
DH1 5TW Tel. 0191-333 2440
Fax. 0191-333 2679
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