Is it possible that the patient was treated during
tranplantation or during a rejection episode with
antibodies from another animal species? If so she would
have developed antibodies to this species that could now
be cross-reacting in your immunoassay.
On Thu, 10 Jun 99 14:27:21 +0100 "Dr. Janet McIlroy"
<[log in to unmask]> wrote:
> Does anyone still have bioassay for PTH?
> I have a patient with steroid-induced osteopenia who had
> renal transplant in 1988. She is normocalcaemic with serum
> creat of 160-180umol/l. Her 25OHD is a little low at
> 11nmol/l with modestly raised tALP at 310 u/l (80-280).
> However PTH has been grossly elevated on 2 occasions 1
> month apart [63 and 93pmol/l by Immulite method
> (RR:1.3-7.6)].I think this is too high for straightforward
> secondary hyperparathyroidism and wonder if what is being
> measured is biologically active. "Dr Janet
> McIlroy"<[log in to unmask]
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pamela riches
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St. Georges Hospital Medical School
Opinions expressed those of the author and not the institution
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