Our lab is urgently required to switch to gel-barrier tubes for routine
biochemistry tests. Could anyone share their experience on the effect of
separator gel with assays of endocrine hormones, therapeutic drugs and so
forth? And paricularly on aspects of degree of analytical variation and
time-related stability.
Some analytes like estradiol, progesterone, carbamazepine etc have
documented prone to silicone interference. Providing two types of clotted
blood containers surely will complicate the blood collection procedure.
Should we take a draconian line to limit SST for routine chemistries and
plain tube for other serum assays; or adopt a more lax policy to smooth out
the blood taking process, provided that the potiential variation is under
control or made known to clinicians ?
Any help gratefully received.
Hiu
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iuyp
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