John,
I note with interest your problem with Vancomycin on the TDx in patients
with severe liver disease. I am reminded of some studies we did many years
ago into DLIS in these patients. As well as measuring some digoxin
immunoreactive material, there was a change in the background seen on the
TDx instrument. It may be valuable to look at the raw data from the
instrument as I suspected at the time (as I say many years ago) that there
was something that interfered non-specifically in the TDx system.
Best regards,
Graham Jones
Staff Specialist in Chemical Pathology
St Vincent's Hospital, Sydney
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