Have to say I don't really see the advantage of POCT here if a core laboratory assay is available. Yes TAT may be slightly quicker but for most PE pathways I'm not sure it adds very much. The woman will often still need bloods for other routine biochem and urine for protein. Plus less training/governance etc to worry about
Stuart
-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of GRAY, Yusuf (UNIVERSITY HOSPITALS OF DERBY AND BURTON NHS FOUNDATION TRUST)
Sent: 22 April 2020 14:48
To: [log in to unmask]
Subject: FW: PlGF testing
Hi All,
I think the 18 minutes refers to how long the assay takes on the analyser module and is not the TAT for that assay. You should compare the TAT from collection to results for each and I think you will find the POC assay wins hands down.
KR
Yusuf Gray
Biomedical Scientist Team Manager - POCT | Pathology - Blood Sciences
T: 01332 788537 | M: 0782 547 9085
Together Everyone Achieves More
-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Andrea Horvath (NSW Health Pathology)
Sent: 22 April 2020 14:22
To: [log in to unmask]
Subject: Re: PlGF testing
Thanks Sally - my staff says the Roche assay is about 18 mins too, so the TAT does not seem to be much worse than with the 15 min "POC" version.
Best, Rita
________________________________________
From: Clinical biochemistry discussion list <[log in to unmask]> on behalf of BENTON, Sally (ROYAL SURREY COUNTY HOSPITAL NHS FOUNDATION TRUST) <[log in to unmask]>
Sent: Wednesday, 22 April 2020 23:14
To: [log in to unmask]
Subject: Re: PlGF testing
Hi Andrea,
Based on the very many responses I've received (thank you everyone), lots of labs that selected the Quidel test are actually doing the analysis in the lab and not at the point of care.
Thanks
Sally
Sally C Benton FRCPath
Consultant Biochemist/ Hub Director,
Clinical Biochemistry, Royal Surrey County Hospital/ NHS Bowel Cancer Screening South of England Hub Berkshire and Surrey Pathology Services Joint venture between Ashford & St Peter's Hospital NHS Foundation Trust, Frimley Health NHS Foundation Trust, Royal Berkshire NHS Foundation Trust and Royal Surrey Hospital NHS Foundation Trust Postal address NHS Bowel Cancer Screening Hub, 20 Priestley Road, Surrey Research Park, Guildford Postcode GU2 7YS
Tel: 01483 409850
PA: Kate Randall [log in to unmask] Tel 01483409854
Email: [log in to unmask]
www.berkshireandsurreypathologyservices.nhs.uk
-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Andrea Horvath (NSW Health Pathology)
Sent: 22 April 2020 13:44
To: [log in to unmask]
Subject: Re: PlGF testing
Hi, in Australia most labs that do preeclampsia testing use the PLGF/sFlt-1 ratio mostly by a Roche method. I am a bit puzzled how the Quidel test is used at the POC if it needs EDTA plasma. So you have centrifuges in Maternity units? If any labs in the UK have a diagnostic protocol for this POC test and device, could you pls kindly share it with us down under?
Best regards, Rita
Andrea Rita Horvath
Clinical Director | NSW Health Pathology Department of Clinical Chemistry and Endocrinology Level 4 Campus Centre The Prince of Wales Hospital Barker Street, Randwick, NSW 2031 Sydney, Australia Tel 02 9382 9078 | Fax 02 9382 9099 | Mob 0404 027 843 [log in to unmask] www.pathology.health.nsw.gov.au
________________________________________
From: Clinical biochemistry discussion list <[log in to unmask]> on behalf of GLOVER, Sarah (HARROGATE AND DISTRICT NHS FOUNDATION TRUST) <[log in to unmask]>
Sent: Wednesday, 22 April 2020 18:33
To: [log in to unmask]
Subject: Re: PlGF testing
Hi,
We are looking to implement the Quidel test within our Maternity unit.
This project was on hold due to a lot issue with the reagents. Since this has been resolved, the POCT team have been focussing their efforts on supporting the COVID response but we are hoping to get it back on track when things return to some level of normality.
Kind Regards
Sarah
-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Andy Kerry
Sent: 22 April 2020 09:26
To: [log in to unmask]
Subject: Re: PlGF testing
We've had recent local interest to measure this as well so all really helpful and thanks for posting your initial query Sally. For those of you using or looking at the Quidel Triage method could I confirm are you performing the test in the lab or have any of you looked at/been been able to perform this at Point of Care e.g in Maternity?
It looks it is 15 mins per test, so taking into account QC and requirement for EDTA plasma these would all be important factors.
Many thanks,
Andy
Andy Kerry
Consultant Clinical Scientist
Dept of Clinical Biochemistry, Clyde Sector Royal Alexandra Hospital
0141 314 6657
Inverclyde Royal Hospital
01475504443
e [log in to unmask]
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------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry.
Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual who posts and they are solely responsible for all message content. The ACB does not monitor posts.
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