Dear Ariadna,
that shouldn’t be necessary (or even good). There is a rigid body movement model inside topup that will take care of any misalignment between the two images with different PE-polarities.
Jesper
> On 26 Jun 2018, at 10:25, Ariadna Albajara Saenz <[log in to unmask]> wrote:
>
> Dear FSL experts,
>
> Someone recommended me to coregister on SPM the DTI (reverse phase-encoding) scan to the DTI (forward phase encoding) scan prior to doing TOPUP on FSL.
> What do you think about this?
>
> Thank you in advance,
>
> Ariadna
>
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