Dear Maria,
you can try the following tool without guarantee and support:
http://www.neuro.uni-jena.de/rSPM/rSPM_41.zip
This toolbox is using deformation-based morphometry to analyze cross-sectional as well as longitudinal rat data:
http://www.neuro.uni-jena.de/pdf-files/Gaser-NI12.pdf
Best,
Christian
On Wed, 18 Oct 2017 11:40:35 +0200, Maria Elisa Serrano Navacerrada <[log in to unmask]> wrote:
>Good morning,
>
>I have to evaluate the structural modification through the time (young to adult, 4 scanners, T2 structural) of Sprague Dawley (rat) brain, due to a neurotoxic product who is going to deteriorate the brain. I have never used SPM, so I have some questions:
>- Can I compare the brain evolution of a normal rat (control) with a rat injected with this product with SPM?
>- Is there a mask for brain rat to just evaluate Gray matter? I saw this tool in C57 mice, but I don't know if there is one for Sprague Dawley rats
>- Which is the best statistical analysis with SPM? Can I do a Mixed Model Repeated Measures?
>
>Thank you for your time and your advices
>
>
>Maria Elisa
>
>Maria Elisa Serrano Navacerrada
>PhD Student Preclinical Imaging
>Bât. B30 Centre de recherches du cyclotron
>Quartier Agora
>allée du 6 Août 8
>4000 Liège 1
>Belgique
>Tél.:+32 4 3662328 E-mail: [log in to unmask]
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