Yes, it is very possible. First you need to calculate the average cortical thickness in each voxel. You can do this in Matlab, or with SPM I am sure, depending on your file format. Then you can treat this as any other overlay file (assuming you make an nii file or similar) and scale by color, as you could for a t-map for example.
Do you specifically need help calculating the mean? What format is your cortical thickness data in?
Colin Hawco, PhD
Neuranalysis Consulting
Neuroimaging analysis and consultation
www.neuranalysis.com
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-----Original Message-----
From: SPM (Statistical Parametric Mapping) [mailto:[log in to unmask]] On Behalf Of Travis Beckwith
Sent: September-12-17 12:14 PM
To: [log in to unmask]
Subject: [SPM] Cortical Thickness Distribution Map
Hi,
I am curious if there is a way to generate a color map display for a human brain representing the mean cortical thickness of a group. I have attached two images as examples of what I would like to generate. I don't know whether it is possible, an earlier post from Christian Gaser suggests that it cannot be estimated using CAT12 (https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=SPM;ab33665f.1708). I also feel like the Zhuang_2017 image might just be a display of the t-maps or beta-maps and not represent actual thickness. Any help would be appreciated.
Narr_2005 is figure 1 from:
Narr, K.L., Toga, A.W., Szeszko, P., Thompson, P.M., Woods, R.P., Robinson, D., Sevy, S., Wang, Y., Schrock, K. and Bilder, R.M., 2005. Cortical thinning in cingulate and occipital cortices in first episode schizophrenia. Biological psychiatry, 58(1), pp.32-40. (http://www.sciencedirect.com/science/article/pii/S0006322305004294?via%3Dihub)
Zhuang_2017 is figure 2 from:
Zhuang, Y., Zeng, X., Wang, B., Huang, M., Gong, H. and Zhou, F., 2017. Cortical Surface Thickness in the Middle-Aged Brain with White Matter Hyperintense Lesions. Frontiers in aging neuroscience, 9. (http://journal.frontiersin.org/article/10.3389/fnagi.2017.00225/full)
Thanks,
Travis
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