Hi Mandy
I remember this being reported when I was a trainee at Nottingham city hospital, indeed they had the following in their SOP.
‘In some samples it may not be possible to rely on the results produced due to variation in the internal standard peak height. If the internal standard peak height is increased in comparison with the rest of the batch, it may be due to the presence of a co-eluting peak. (Anecdotal evidence [private communication May 2012] suggests this may be from chilli spices.) The first time this is observed in a patient sample it should be referred to Leicester Royal Infirmary at the address below for analysis by LC/MS/MS.’
Maybe someone from NUH can provide more info?
Thanks
Stephen
Stephen Gibbons PhD, DipRCPath
Principal Clinical Scientist in Endocrinology
St James University Hospital
Leeds
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