We are currently adding a comment to non-fasting TG to say that the reference applies for fasting only. I don't think there is a separate Read code for non-fasting TG anymore? The latest PMIP release appears to include only one code (44e.. : Plasma triglyceride level), which would make reporting a separate ref range tricky.
Stuart
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From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Iversen Andrew (BRIGHTON AND SUSSEX UNIVERSITY HOSPITALS NHS TRUST)
Sent: 02 July 2015 09:02
To: [log in to unmask]
Subject: Re: Lipid profile
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The LDL cholesterol calculation requires the TG present to be in VLDL of normal composition. This means fasting.
We are retaining our existing fasting and non-fasting lipid profiles, but adding TG to the non fasting profile and non HDL cholesterol calculations to both profiles.
Does anyone have a good reference range for non-fasting TG?
Kind regards
Andrew
-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Neely, Dermot
Sent: 01 July 2015 17:19
To: [log in to unmask]
Subject: Re: Lipid profile
NICE CG181 doesn't recommend removal of LDL-cholesterol and total cholesterol/HDL ratio from the lipid profile report Total:HDL-Cholesterol is required for QRisk2 assessment LDL-C is required for diagnosis of FH but should only be included on reports when the sample was fasting and Trigs<4.5 I don't see the point on making patients on statin fast to assess treatment response, non-fasting non-HDL-C is perfectly adequate.
Dermot Neely
-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Stephen Davis (Cwm Taf UHB - Biochemistry)
Sent: 01 July 2015 11:26
To: [log in to unmask]
Subject: Re: Lipid profile
Here in Wales we have recently added non-HDL cholesterol to the lipid profile but have removed neither LDL-C nor the cholesterol:HDL-C ratio. An automated comment goes out with the result explaining that NHDL-C is included in the profile in accordance with NICE CG181
Steve
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Principal Biochemist
Biochemistry
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-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Mohammad Al-Jubouri
Sent: 01 July 2015 10:34
To: [log in to unmask]
Subject: Lipid profile
Dear All,
Nice guidance CG181 suggests measuring & reporting lipid profile on non fasting sample as below:
Lipid profile includes:
Total cholesterol
HDL cholesterol
Non-HDL cholesterol
Triglycerides
This means removal of LDL-cholesterol and total cholesterol/HDL ratio from the lipid profile report.
For those who have already done so, were there any feedback from the users on remving LDL and total cholesterol/HDL ratio? Do you include any autocomments regarding non-HDL cholestrol to guide the users?
I am also interested in what you currently include in your lipid profile reports, if you could let me know these please then I will be able to collate them and report back to the mailbase.
Many thanks
Mohammad
Dr. M A Al-Jubouri, MB ChB, MSc, EurClinChem, FRCP Edin, FRCPath Consultant Chemical Pathologist
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