And allergy specialists still use the term RAST, when the tests are now
non-isotopic.
Mike
-----Original Message-----
From: Clinical biochemistry discussion list
[mailto:[log in to unmask]] On Behalf Of David Bullock
Sent: 28 August 2013 15:29
To: [log in to unmask]
Subject: Re: What is an RIA?
And our colleagues in analytical chemistry use the term "ELISA" for any
sort of immunassay, independent of whether it's enzyme-linked or
immunosorbent
I blame the reviewers . . .
Best wishes
David
________________________________
From: Clinical biochemistry discussion list
[[log in to unmask]] on behalf of Prof TS Pillay
[[log in to unmask]]
Sent: 28 August 2013 15:17
To: [log in to unmask]
Subject: What is an RIA?
Dear members of the mailing list,
I have a simple (perhaps trivial even) but important question.
I have come across several relatively recent review articles in good
journals where reference is made to the Diasorin Liaison
nonisotopic/nonradioactive Vit D assay as a "radioimmunoassay" because
it is based on the format of a previous RIA, i.e. uses an antibody as
the capture reagent and a radiolabelled analyte analogue to compete. The
new assay uses Chemiluminescence and Diasorin calls it a CLIA, which is
fine.
However, the articles insist on calling the CLIA assay an "RIA" even
and another assertion is made (not by the same source) that since
chemiluminescence is a form of radiation, the RIA term still applies.
I would be grateful for collective thoughts on this.
Thanking you in advance
Tahir Pillay
--
Prof T.S. Pillay, MBChB, PhD, FRCPath, FCPath
Professor & Head
Department of Chemical Pathology
Faculty of Health Sciences
University of Pretoria
Pretoria
South Africa
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This is an open discussion list for the academic and clinical community working in clinical biochemistry.
Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content.
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