The rôle of metformin in lactic acidosis is controversial.
What other factors that could have caused the deterioration were originally present, and which are present now?
Jonathan
On 19 Jun 2013, at 18:04, Jones, Alison wrote:
> Advice from the collective brain please - I don't have too many details
> to hand, I'm afraid.
>
> Patient on ICU. Metformin stopped 36h ago, but lactic acidosis getting
> progressively worse (most recent lactate >11 mmol/L). Creatinine =
> 130umol/L.
>
> Is lactic acidosis likely to be due to metformin (i.e. can effects be
> persistent) or should we be looking for another cause?
>
> Many thanks
>
> Alison Jones
>
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