I would think that you might raise some eyebrows using ROIs obtained using
FSL's FLIRT in data normalized using SPM's non-linear (Dartel?) tool, due
to the big potential difference between linear (affine) and non-linear
approaches. Of course, it would depend on the anatomical precision that
you want/need for your particular study and whether the ROIs involve
regions that are particularly sensitive to non-linear registration.
cheers,
-MH
--
Michael Harms, Ph.D.
-----------------------------------------------------------
Conte Center for the Neuroscience of Mental Disorders
Washington University School of Medicine
Department of Psychiatry, Box 8134
660 South Euclid Ave. Tel: 314-747-6173
St. Louis, MO 63110 Email: [log in to unmask]
On 11/28/12 11:43 AM, "MCLAREN, Donald" <[log in to unmask]> wrote:
>Dear SPM/FSL users,
>
>It seems that there are several templates (SPM v FSL) as well as
>different normalization routines that could result in slight
>variations of the localization of the results. Do I need to worry
>about these small differences between methods?
>
>In particular, I want to know if I can take regions defined in a study
>using FLIRT in FSL and use them in my study that has been processed
>with SPM's non-linear normalization tool. Can I use them as is or is
>there a transform that can I compute and/or apply to the ROIs to get
>them into the SPM normalized space.
>
>Thank you in advance for your input.
>
>Best Regards, Donald McLaren
>=================
>D.G. McLaren, Ph.D.
>Research Fellow, Department of Neurology, Massachusetts General Hospital
>and
>Harvard Medical School
>Postdoctoral Research Fellow, GRECC, Bedford VA
>Website: http://www.martinos.org/~mclaren
>Office: (773) 406-2464
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