Dear Colleagues,
I hope the Mass Spec experts among you can help us.
We use Li Hep for most paediatric assays because the yield of plasma is significantly greater than for serum from the same volume of whole blood.
However, there is some concern about using Li Hep samples in tandem MS assays beacuse iof the relatively high concentration of Lithium in the samples.
What I would like to know is, is it possible to use LiHep plasma for 25Hydroxy Vitamin D analysis, without detriment to the result (ie that results are commutable with results from serum and the same reference intervals can be used) or to susequent 25 Hydroxy Vit D assays on the same instrument using serum (i.e. there is no suppression of signal etc)?
Thanks in advance
Chris
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical community working in clinical biochemistry.
Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
Green Laboratories Work
http://www.laboratorymedicine.nhs.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
|