Hi Ted,
Here are a few studies looking at trial/review article conclusion by
funding source...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC34722/?tool=pubmed
http://www.nejm.org/doi/full/10.1056/NEJM199801083380206#t=articleMethods
http://archinte.ama-assn.org/cgi/reprint/154/2/157
http://www.bmj.com/content/340/bmj.c1344?view=long&pmid=20299696
http://www.ncbi.nlm.nih.gov/pubmed/12775614
My take on conflict of interest is that you can't really tell from the
statement whether someone's relationships are likely to affect their
conduct. For this reason, I think it is much better if medical
education and review articles (perhaps eventually trials) are
written/delivered by people without conflicts of interest.
CoI statement: I am currently trying to set up a scheme to accredit
medical education delivered without industry funding by people without
conflict of interest. I also work on a trial that has received some
funding from GSK.
Best wishes,
Tom
On 8 August 2012 15:44, Ted Harding <[log in to unmask]> wrote:
> On 08-Aug-2012 12:50:19 Dr. Carlos Cuello wrote:
>> Interesting question
>>
>> http://the-scientist.com/2012/08/07/opinion-bias-is-unavoidable/
>> --
>> Carlos A. Cuello-García, MD
>
> Interesting question indeed.
>
> My take on Conflict of Interest declarations is that they
> say what they say, no more, no less, neamly that X has
> received funding from Y.
>
> This does not imply that, by declaring the interest, X is
> implicitly declaring that conduct, interpretation and
> publication have not been influenced by the funding, and
> were entirely objective.
>
> Nor does it imply that, by accepting the funding, X has
> been influenced, or has been biased, in favour of any
> particular outcome.
>
> Either interpretation may be the correct one.
>
> The real question is: Which interpretation is the more probable?
>
> Which leads on to an EBH-question:
>
> What studies are there which compare the outcomes of funded
> trials with each other, with funding agency as predictive
> covariate, where such trials refer to outcomes for a particular
> condition and involve competing treatments?
>
> Best wishes to all,
> Ted.
>
> -------------------------------------------------
> E-Mail: (Ted Harding) <[log in to unmask]>
> Date: 08-Aug-2012 Time: 15:44:53
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