Hi Hilda
I'd want to include the difference between disease oriented outcomes (DOOs ie surrogates such as HbA1c, LDL, peak flow, etc) and patient oriented outcomes (POOs) ie whether this treatment helps people live longer or better. I'm sure members of this group can think of many examples of where DOOs have misled eg rosiglitazone, torcetracib (that's a good one to look at!), etc. And further back, beta blockers in HF, lidocaine in arrhythmias, etc.
Cheers
Andy
Andy Hutchinson MEd, Pharmacist
Education and Development Manager
National Prescribing Centre
Provided by the National Institute for Health and Clinical Excellence
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NICE Annual Conference 2012, 15-16 May, Birmingham, UK
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----- Original Message -----
From: Bastian, Hilda (NIH/NLM/NCBI) [C] [mailto:[log in to unmask]]
Sent: Saturday, March 10, 2012 04:25 PM
To: [log in to unmask] <[log in to unmask]>
Subject: Top 3 (or so) essential clinical epi concepts
G'day!
I'm working on a list of top 3 (with top 5 and top 10 too) basic concepts patients, journalists & clinicians need not to understand to protect themselves from the data/health claims that commonly mislead. Would really appreciate thoughts & all personal favourite lists like this.
At the moment my personal list goes like this:
1. Correlation vs causation
2. Relative risks without context
3. Increasing survival rates vs increasing length of life
Thoughts/resources gratefully received. (Have a great weekend!)
Many thanks!
Hilda
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