Hi,
I did some work on breast implants when at Broomfield hospital (soya oil implants I believe) where I was trying to look at changes in the lipids in the implants as part of another recall (perhaps this is a message in itself!) A large proportion of them had evidence of rupture and evidence of infiltration. Perhaps there are some changes in inflammatory markers but otherwise as indicated laboratory testing was deemed most unhelpful.
The most interesting aspect of the whole project was the wide variance in the size of implant!
Cheers
Craig
Craig Webster
Consultant Clinical Scientist
Birmingham Heartlands Hospital
Birmingham
B95SS
On 10 Jan 2012, at 10:23, Nick Miller wrote:
> Thanks for that Johnathan.
>
> I agree that lab investigations are not indicated in a situation where
> most sane people would want to have the implants removed - the
> question being "who is going to pay for it?"
>
> However, this is by no means a new issue: leakage of silicon and
> consequent sensitisation is not confined to subjects with the poor
> quality implants that have recently been in the news. Sometimes women
> are referred with a variety of health problems and are unaware that
> silicon sensitisation is the root cause - hence the need for a lab
> test.
>
> Nick Miller
> London
>
> On 10/01/2012, Jonathan Kay <[log in to unmask]> wrote:
>> DH Letter to Professionals:
>> http://www.dh.gov.uk/health/2012/01/pip-breast-implants-letters-to-professionals/
>>
>> DH Interim Report from the Expert Group:
>> http://www.dh.gov.uk/health/2012/01/pip-implants-interim-report/
>> Annex E of this contains the clinical guidance. It does include looking for
>> evidence of rupture. In the main body of the report it says "... some
>> ruptures – perhaps as many as 2 in 3 – do not result in clinical signs or
>> symptoms, and can only be detected by scanning or by explantation (removal).
>> " The report does not mention laboratory investigations.
>>
>> Jonathan
>>
>> On 9 Jan 2012, at 14:55, Sarah Mapplebeck wrote:
>>
>>> I've had a phone call from one of our local GPs. Several patients have
>>> turned up asking for their blood tests as they have PIP implants. Surgeons
>>> are sending patients to their GPs who don't know what to do.
>>>
>>> Are we meant to measure silcone in these patients and if so, any ideas on
>>> the laboratory providing this? What are others doing?
>>>
>>> Thanks, Sarah
>>>
>>
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