Thank you to all who responded to this. Suggestions included measuring urine amylase - it was more the other chemistries which concerned me as abdominal scanning could perhaps be used although I don't know the diagnostic accuracy of this for pancreatitis.
Other suggestions were to ultracentrifuge, run using 'dry chemistry' analyser, refridgerate and run infranatant and dilute the sample to dilute out the interference. We had considered these but no ultracentrifuge or easy access to dry chemistry analysers and were worried about the validity of the latter two so it was it was helpful to see that others would also try this.
We did serial dilutions and obtained fairly linear results. We have also refridgerated and run the infranatant. The patient was in fact very well clinically but did have significantly raised transaminase and LD and has now been discharged.
Dr Anne Tarn
Consultant Chemical Pathologist
Croydon University Hospital
Tel: 0208 401-3024
email: [log in to unmask]
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical community working in clinical biochemistry.
Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
Green Laboratories Work
http://www.laboratorymedicine.nhs.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
|