The VEPRO trial: a cross-over randomised controlled trial comparing 2
progressive lenses for patients with presbyopia.
Boutron I, Touizer C, Pitrou I, Roy C, Ravaud P.
Source
INSERM, U738, Paris, France, Université Paris, 7 Denis Diderot, UFR de Médecine,
Paris, France, AP-HP, Hôpital Bichat, Département d'Epidémiologie,
Biostatistique et Recherche Clinique, Paris, France.
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Best,
Paul E. Alexander
----- Original Message ----
From: Douglas Badenoch <[log in to unmask]>
To: [log in to unmask]
Sent: Tue, July 26, 2011 4:47:29 AM
Subject: Re: CONSORT statement and crossover trials
Dear colleagues
It strikes me that this discussion is exactly the sort of reason why we
recently added a Library of Examples to the CONSORT Statement website.
http://www.consort-statement.org/consort-library/
The idea is that people can submit examples of good reporting here.
If someone is aware of an example of a flow diagram (or other CONSORT
item) from a crossover trial they should feel encouraged to submit it to
the CONSORT Library for all to see.
cheers
Douglas
On 26/07/2011 08:41, Iveta Simera wrote:
> The CONSORT 2010 checklist applies to all randomised trials. A few specific
>additional issues need to be addressed for designs other than the two arm
>parallel group design. Unfortunately our planned publication describing specific
>recommendations for reporting crossover trials has not yet been completed.
>
> The main issues to consider for crossover trials relate to the rationale for
>using the design (including an expectation of no important carry over effect
>from one treatment period to the next), the description of any washout period,
>the use of statistical methods for paired data (in design, analysis, and
>presentation of results), and description of any investigation of the impact of
>the order of receiving interventions or carry-over effects.
>
> It is not difficult to modify the flow diagram appropriately and we have seen
>many published examples.
>
> Doug Altman
> Centre for Statistics in Medicine
> University of Oxford
> Wolfson College Annexe
> Linton Road, Oxford OX2 6UD
> www: http://www.csm-oxford.org.uk/
>
> CONSORT 2010 Statement: www.consort-statement.org
> EQUATOR Network - resources for reporting research: www.equator-network.org
> Trials journal: www.trialsjournal.com
--
Mr Douglas Badenoch
Director, Minervation Ltd
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