I would disagree. Levels this high are frequently seen in cases of ascites.
Michael
-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Peadar Mcging
Sent: 18 July 2011 15:55
To: [log in to unmask]
Subject: Re: CA125
David,
In a case like this I would speak to the team, both to add a cautionary note (but in a discussion where I can better ascertain the particular situation pertaining to the individual) and to inform them of how high the result is. While lots of situations mentioned in some other replies often cause a high CA125, my own experience of levels this high is that it is cancer, especially ovarian cancer, more often than it is not. On occasions I add CEA (if not already requested) as this can be of help (e.g. high CEA and CA125 of this order in colon cancer).
best wishes.
Peadar
Dr Peadar McGing, FRCPath EurClinChem,
Principal Biochemist,
Biochemistry Dept., Mater Misericordiae University Hospital,
Eccles Street, Dublin 7, Ireland.
Tel: (+353 1)8032374; Fax: (+353 1)8034781.
-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of David Burgess
Sent: 18 July 2011 15:27
To: [log in to unmask]
Subject: CA125
May I ask your opinion. A 50 y.o. woman, an inpatient on the gynae ward, bleeding p.v. and with ascites and hydronephrosis has a CA125 1500 kU/L (N<35). There are no previous measurements. Should her results be accompanied by a cautionary note e.g. " may be raised in a number of benign conditions including endometriosis, inflammatory pelvic disease and acites"? Also should her results be phoned to the ward?
Regards, David
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