It looks as if something has changed.
Was he 29 when you first saw him or is he 29 now [Has time stood still?
or does he have a picture in the attic?]
What about his triglycerides: has he taken to alcohol, or developed
diabetes...
TIM
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Prof. Tim Reynolds
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Burton Hospitals NHS Foundation Trust
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-----Original Message-----
From: Clinical biochemistry discussion list
[mailto:[log in to unmask]] On Behalf Of Robert Lord
Sent: 24 June 2011 14:32
To: [log in to unmask]
Subject: Possibly need to measure statin in blood?
Comments / advice appreciated -
Have been seeing a 29 year old male for the past 21 yrs
for FH. Chol = 11 off treatment
Was on rosuvastatin 30mg in 2005, Chol = 4.0. Discharged. Re-referred
2010 due to chol increasing to 6.1 on
rosuvastatin 40mg / ezetimibe 10mg.
Tried simvastatin 80 mg and also atorvastatin 80mg since
then. Can't get chol < 7.
Niaspan doesn't work.
Assures me he is compliant with medication - confirmed by
mother in clinic today!
No other medication - no OTC meds or drugs of abuse
Diet = ok. No weight loss. No evidence of malabsorption
U+E/LFT/Glucose/TFT/FBC = normal.
Any ideas?
Should I measure the statin level in his blood to check
compliance - can this be done?
Check for malabsorption even though clinically unlikely?
Anything else!?
Many thanks
Rob
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