Comments / advice appreciated -
Have been seeing a 29 year old male for the past 21 yrs
for FH. Chol = 11 off treatment
Was on rosuvastatin 30mg in 2005, Chol = 4.0. Discharged.
Re-referred 2010 due to chol increasing to 6.1 on
rosuvastatin 40mg / ezetimibe 10mg.
Tried simvastatin 80 mg and also atorvastatin 80mg since
then. Can't get chol < 7.
Niaspan doesn't work.
Assures me he is compliant with medication - confirmed by
mother in clinic today!
No other medication - no OTC meds or drugs of abuse
Diet = ok. No weight loss. No evidence of malabsorption
U+E/LFT/Glucose/TFT/FBC = normal.
Any ideas?
Should I measure the statin level in his blood to check
compliance - can this be done?
Check for malabsorption even though clinically unlikely?
Anything else!?
Many thanks
Rob
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical community working in clinical biochemistry.
Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
Green Laboratories Work
http://www.laboratorymedicine.nhs.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
|