Hi,
A paired sample comparison for 30 neonatal samples in our hospital indicated a positive bias on the Roche omni S when compared with lab method (vanadate oxidase), the results being up to 20 umol/L higher in some cases. The difference did not appear to be concentration related, probably highlighting a calibration issue?
(Page 250 of the abstract pages).
Raf.
Rafaq Azad
Principal Clinical Biochemist / Scientific Coordinator Born in Bradford
Department of Clinical Biochemistry
Bradford Royal Infirmary
Duckworth Lane
Bradford
BD9 6RJ
Tel: 01274 382683
E-mail: [log in to unmask]
http://www.borninbradford.nhs.uk/
>>> Jonathan Kay <[log in to unmask]> 02/04/2011 09:03 >>>
PubMed
http://www.ncbi.nlm.nih.gov/pubmed?term=comparison%20%22blood%20gas%22%20bilrubin
gives 14 hits
Google:
http://www.google.co.uk/search?client=safari&rls=en&q=comparison+%22blood+gas%22+bilrubin
gives 220,000 hits
Would someone like to do a Systematic Review? One for the Scientific Committee?
Jonathan
On 2 Apr 2011, at 08:52, Jonathan Kay wrote:
> Joe has asked the key question. If the methods give the same answer I wouldn't worry about the specimen type being whole blood or skin puncture fluid rather than serum.
>
> There is some previous discussion in the mailgroup:
> https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=ind02&L=ACB-CLIN-CHEM-GEN&P=R346255&1=ACB-CLIN-CHEM-GEN&9=A&J=on&d=No+Match%3BMatch%3BMatches&z=4
>
> Can anyone add relevant publications, device assessments or EQA data?
>
> The NICE guidance is at:
> http://guidance.nice.org.uk/CG98
>
> Jonathan
>
>
>
>
> On 1 Apr 2011, at 17:36, Indovina, Joe [OCDUS] wrote:
>
>> Dear Funmi
>>
>> Your post is intriguing. To me the bigger question is how well does the bilirubin measurement form the Blood Gas analyzer correlate with the clinical laboratory method. If the correlation is different and not clearly defined, confusion in interpretation will be the outcome. The differences may impact classification with the nomogram
>>
>> Joe I
>>
>>
>>
>> From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Akinlade Funmi (RF4) BHR Hospitals
>> Sent: Friday, April 01, 2011 12:36 PM
>> To: [log in to unmask]
>> Subject: Blood gas analyzers & bilirubin
>>
>> Hello all,
>> we recently introduced bilirubin on our blood gas analyzer in NICU. At the moment they have a Pfaff Bilimeter 3 which they've been using on the ward. The recently issued nice guidelines on Neonatal Jaundice mention the use of serum bilirubin to diagnose and follow up babies with jaundice. Does this then rule out the use of blood gas analyzers to measure bilirubin in these babies?
>>
>> Also if your Hospital uses blood gas analyzers to measure bilirubin how is it used on the ward?
>>
>> Kind regards,
>>
>> Funmi Akinlade
>> Barking, Havering and Redbridge University Hospitals NHS Trust,
>> Queen's Hospital, Romford.
>>
>> Barking, Havering & Redbridge University Hospitals NHS Trust: Most Innovative Trust in London 2009
>>
>>
>
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