Hello,
I know at least the following papers on this topic:
---
"High resolution protein structure prediction and the crystallographic
phase problem"
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504711/
"Prospects for de novo phasing with de novo protein models"
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631639/
---
I think it worked on several of their cases, better on
small proteins if I remember well.
Regards,
F.
Kornelius Zeth wrote:
> Dear all,
>
> I was wondering if anybody has used the ROSETTA software to generate a MR model that could subsequently being used successfully for a MR solution case.
>
> The sequence of the protein we work with is relatively small, ~ 85 residues. Crystallization is not very reproducible. Resolution is 1.9 A. Crystals are extremely rare.
>
> I would be grateful for any hints and will send a summary of all personally sent comments to the list.
>
> Thank you and have a nice day
>
> Kornelius
>
> ----------------------------------------------
> Kornelius Zeth
> Max Planck Institute for Developmental Biology
> Dept. Protein Evolution
> Spemannstr. 35
> 72076 Tuebingen, Germany
> [log in to unmask]
> Tel -49 7071 601 323
> Fax -49 7071 601 349
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