I don't know about ideas - but there is an important question: If staff
have never seen any signs of alcohol use, and she has many negative
tests, why are they wasting money testing her?
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Prof. Tim Reynolds
Consultant Chemical Pathologist
Burton Hospitals NHS Foundation Trust
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-----Original Message-----
From: Clinical biochemistry discussion list
[mailto:[log in to unmask]] On Behalf Of McClean, Liz
Sent: 02 July 2010 12:19
To: [log in to unmask]
Subject: FW: false positive urine alcohol
From: McClean, Liz
Sent: 02 July 2010 12:08
To: [log in to unmask]
Subject: false positive urine alcohol
Dear Mailbase
I'd be grateful if anyone could throw some light on a problem we have
come across with urine ethanol testing in a particular patient. This
women has had several positive urine ethanol levels using our Dade
Behring Dimension kit, ranging from 28.5mg/dL to 158mg/dL, she has also
had a couple of negative tests. When we analyse her positive samples on
the ROCHE ethanol method we get an uncharacteristic trace and when
analysed by GC there is no ethanol detected in any of the samples. I
have also analysed her samples on a ramp method on the GC which can pick
up acetone, methanol, ethanol, isopropanol, propan-1-ol and ethylene
glycol and there are no significant peaks at all - even ones not
corresponding to the substances above. ( We have also ran a few other
positive urine ethanol samples from the same centre on the GC and all of
them have checked out the same as the Dimension results, except this
patient.)
The staff monitoring this lady have quizzed her about her use of hand
sanitizers, feminine sprays etc but have drawn a blank. Blood and
breathe alcohols on this lady have also been negative and she the staff
at the hostel where she lives have confirmed that she has never shown
any signs of alcohol use while she has been living with them.
Has anyone any ideas?
Thanks
Liz McClean
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