Dear Martin & Richard
I think a more systematic study would be a nice idea! But this current
request is to garner examples for *teaching*: to illustrate how
treatments can rise (and hopefully fall) despite weak evidence. I think
many of us use the same (now tired) examples, such as flecainide and
HRT, and some newer ones would be helpful - both to save us from
boredom, but also to illustrate that it still happens. For example, the
nesiritide is a good example from this century, with the rise and fall
happening in the last decade. Also, its helpful to have examples from a
range of areas.
The references to the definitive evidence (plus any supplementary
articles) would be very helpful - thanks!
I'll post the full list of suggestions on Monday.
Paul Glasziou
Richard Nicholl wrote:
> agree..
> correct me if wrong ( I am merely a neonatal paediatrician) BUT I
> believe there /is/ a _treatment effect_ for
> high dose Vit C and cold ( reduces length of symptoms)
> antiobiotics and SORE THROAT (as opossed to "common cold"- whatever
> that is....people may want rid of their symptoms rather than their
> diagnostic label)
> I think folk should provide references to justify their (negative)
> evidence, including me but I am between pts in outpatients!
> interesting idea though...will try to get some paediatric ones
>
> ------------------------------------------------------------------------
> *From:* Evidence based health (EBH) on behalf of Martin Dawes, Dr.
> *Sent:* Fri 11/06/2010 12:01
> *To:* [log in to unmask]
> *Subject:* Re: Popular but ineffective treatment?
>
> what worries me about this is the highly anecdotal way it is happening
> What about taking this methodically
> looking at the top 100 prescriptions, and the top 100 over the counter
> medications, and the top 100 mechanical Txs (ultrasound for example)
> and assessing them?
> Martin
>
>
> On 11 Jun 2010, at 02:33, Lubna Al-Ansary wrote:
>
> Bed rest for acute back pain
> Routine D & C for missed abortion
> Lidocaine for arrythmia post MI
>
>
> Sent from my iPod
> Dr Lubna Al-Ansary
>
> Begin forwarded message:
>
> From: Tom Jefferson
> <[log in to unmask]<mailto:[log in to unmask]>>
> Date: ١١ يونيو، ٢٠١٠ GMT+٠٣:٠٠ ٩:٠٢:٥٤ ص
> To: <mailto:[log in to unmask]>
> [log in to unmask]<mailto:[log in to unmask]>
> Subject: Re: Popular but ineffective treatments?
> Reply-To: Tom Jefferson
> <[log in to unmask]<mailto:[log in to unmask]>>
>
> Vit C for the commom cold (you have to take tons of the stuff and then
> you get gallstones because of bile low PH) - poor Linus Pauling
>
> On 11 June 2010 07:58, Bruce Arroll
> <<mailto:[log in to unmask]>[log in to unmask]<mailto:[log in to unmask]>>
> wrote:
> Dear paul and chris
>
> Cough suppressants for the common cold (a billion dollar industry)
> Antibiotics for the acute common cold
> Routine episiotomy in low risk pregnancies
>
>
> bruce
>
> -----Original Message-----
> From: Evidence based health (EBH)
> [mailto:<mailto:[log in to unmask]>[log in to unmask]<mailto:[log in to unmask]>]
> On Behalf Of Chris Del Mar
> Sent: Friday, 11 June 2010 12:23 p.m.
> To: <mailto:[log in to unmask]>
> [log in to unmask]<mailto:[log in to unmask]>
> Subject: Re: Popular but ineffective treatments?
>
> Paul
>
> 1 tidying lavage arthroscopy for OA knee
> 2 vertebroplasty for painful osteoporotic vertebral fractures
> (Buchbinder R, N Engl J Med 2009;361:557-68)
>
> Chris
>
> -----Original Message-----
> From: Evidence based health (EBH)
> [mailto:<mailto:[log in to unmask]>[log in to unmask]<mailto:[log in to unmask]>]
> On Behalf Of Paul Glasziou
> Sent: Friday, 11 June 2010 12:31 AM
> To: <mailto:[log in to unmask]>
> [log in to unmask]<mailto:[log in to unmask]>
> Subject: Popular but ineffective treatments?
>
> Dear All
> Following the influenza discussion, I wanted to ask for ideas of
> treatments that became (or are) popular but where evidence showed them
> ineffective.
> For example,
> 1. Autologous bone marrow transplantation for breast cancer
> 2. Evening primrose oil for menstrual symptoms
> 3. Neuroblastoma screening in infants
> 4. HRT for prevention of CVD in menopause
> These examples are from Testing Treatments which is downloadable (free
> pdf!) at:
> <http://www.jameslindlibrary.org/testing-treatments.html>http://www.jameslindlibrary.org/testing-treatments.html
> The book is being updated, and we are looking for new examples.
> I will compile the list and send to everyone.
> If you can include the reference (or clues to it) I'd be grateful
> Many thanks
> Paul Glasziou,
> CEBM
>
>
>
> --
> Dr Tom Jefferson
> Scientific Editor PLoS ONE
> Reviewer, Cochrane Acute Respiratory Infections Group
> tel 0039 3292025051
>
>
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