Those WHO are interested in the development of HbA1c in diagsnosis of
diabetes should read the January issue of Clinical Chemistry - and do
not miss the editorial by Boyd and Bruns!
Anders Kallner
----- Original Message -----
From: Martin Holland <[log in to unmask]>
Date: Saturday, February 27, 2010 10:28 am
Subject: Re: Health Screening
To: [log in to unmask]
> Hi Richard,
>
> Thanks for that very useful algorithm. How is it that the DOH has
> managed to sidestep the World Health Organisation's
> recommendations on the diagnosis of diabetes which, if I remember
> correctly, only uses fasting and 2 hour glucose?
>
> Perhaps the DOH does not know WHO they are? Can we trump DOH with
> WHO?
> Regards,
>
> Martin.
>
> ----- Original Message -----
> From: Harris Richard
> To: [log in to unmask]
> Sent: Friday, February 26, 2010 2:30 PM
> Subject: Re: Health Screening
>
>
> Michael
>
>
>
> Is the GP referring to this section of the NHS health check
> programme for vascular diseases, which contains an algorithm for
> 'diagnosis of diabetes' following BMI >30?
>
>
>
>
>
>
>
> Several of our local GP surgeries have been following this and
> sending in HbA1c samples instead of fasting plasma glucoses, the
> chart states either is acceptable as a screen. It does then
> recommend an OGTT if Hba1c 42 - 48mmol/mol but it's still possible
> to measure Hba1c on 2 separate occasions and if both are
> >48mmol/mol (6.5%) in a non symptomatic patient with a BMI >30
> then a diagnosis of diabetes can be made!!
>
>
>
> Are other members aware of this? How were the cut off values
> determined? What advice can you give when guidelines have been
> published by DOH?
>
>
>
> Richard
>
>
>
> Dr Richard Harris
>
> Senior Biochemist
>
> Kettering General Hospital
>
>
>
> -----Original Message-----
> From: Clinical biochemistry discussion list [mailto:ACB-CLIN-
> [log in to unmask]] On Behalf Of Colley, Michael
> Sent: 24 February 2010 17:17
> To: [log in to unmask]
> Subject: Re: Health Screening
>
>
>
> I've just been informed by a GP that they've been instructed to
> measure
> HbA1 in patients with high BMI as a screen for Diabetes.
>
>
>
> I was under the impression that HbA1 was so variable between
> individuals
> that it had not been shown to be useful for screening (except in
> the USA
>
> !!).
>
>
>
> Have I missed out on a change of opinion about its usefulness? Can
>
> anyone give me references?
>
>
>
> Michael
>
>
>
>
>
> Dr C M Colley
>
> Consultant Chemical Pathologist
>
> Great Western Hospital
>
> Swindon SN3 6BB
>
>
>
>
>
>
>
> Great Western Hospitals NHS Foundation Trust Great Western
> Hospital Marlborough Road Swindon
>
> SN3 6BB
>
> Tel 01793 60 40 20
>
>
>
> http://www.gwh.nhs.uk
>
>
>
> Register to become a member of the Trust at
> https://members.gwh.nhs.uk
>
>
> This message and any files transmitted with it are confidential
> and intended solely for the individual(s) addressed.
>
> If you believe you have received this e-mail in error,
> disclosing, copying, distributing or retaining this message, or
> any part of it, is strictly prohibited; please notify the sender
> immediately and delete it from your system.
>
> Any views or opinions presented are solely those of the author
> and do not necessarily represent those of Great Western Hospitals
> NHS Foundation Trust.
>
> All messages sent by the Trust are checked for viruses but this
> does not, and cannot, guarantee that a virus has not been
transmitted.
>
> The Trust accepts no liability for any damage caused by any
> virus transmitted with this e-mail.
>
>
>
> ------ACB discussion List Information--------
>
> This is an open discussion list for the academic and clinical
> community working in clinical biochemistry.
>
> Please note, archived messages are public and can be viewed via
> the internet. Views expressed are those of the individual and they
> are responsible for all message content.
>
> ACB Web Site
>
> http://www.acb.org.uk
>
> Green Laboratories Work
>
> http://www.laboratorymedicine.nhs.uk
>
> List Archives
>
> http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
>
> List Instructions (How to leave etc.)
>
> http://www.jiscmail.ac.uk/
>
> ------ACB discussion List Information-------- This is an open
> discussion list for the academic and clinical community working in
> clinical biochemistry. Please note, archived messages are public
> and can be viewed via the internet. Views expressed are those of
> the individual and they are responsible for all message content.
> ACB Web Site http://www.acb.org.uk Green Laboratories Work
> http://www.laboratorymedicine.nhs.uk List Archives
> http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List
> Instructions (How to leave etc.) http://www.jiscmail.ac.uk/
>
> ------ACB discussion List Information--------
> This is an open discussion list for the academic and clinical
> community working in clinical biochemistry.
> Please note, archived messages are public and can be viewed via
> the internet. Views expressed are those of the individual and they
> are responsible for all message content.
> ACB Web Site
> http://www.acb.org.uk
> Green Laboratories Work
> http://www.laboratorymedicine.nhs.uk
> List Archives
> http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
> List Instructions (How to leave etc.)
> http://www.jiscmail.ac.uk/
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical community working in clinical biochemistry.
Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
Green Laboratories Work
http://www.laboratorymedicine.nhs.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
|