Dear all,
I have developed an excel spreadsheet off and on over the last year
which automates the NBA/NOA calculation and interpretations.
I haven't used any of the commercial software available so I don't know
if they offer anything 'extra', but I can't think of anything else that
we would want at present.
I have submitted an abstract for Focus describing it, along with an
unusual case that highlights that clinical interpretation is still of
importance.
I will make this spreadsheet available for others to use free of charge,
in the near future, but if anyone would like to have a look at the
spreadsheet to test it with other spectrophotometers in other labs,
please get in touch as this would be helpful too.
We use a Cecil spec with Datastream software to collect the data on a PC
and then transfer the raw absorbance data into excel, which then does
the rest. I have also tested it with a Beckman DU 800 spec.
I have designed it to follow the Revised UK Guidelines and will:
* Plot scan data - automatically setting the y-axis to 0.1 if max
abs <0.1 or scaling appropriately if >0.1AU
* Finds the absorbance max for the oxyhaemoglobin peak (410-418nm)
* Fits a predicted baseline to the scan
* Calculates NBA/NOA
* Works through the algorithms described in the guidelines to
arrive at the appropriate comment.
* Only if further data is needed will it ask for it (e.g. for
adjusted NBA calc.)
Using this we can perform a CSF bilirubin analysis in less than 10
minutes from start to finish, and are able to print/fax/e-mail scans
directly for clinical validation as desired, with the interpretation
from the guidelines on the scan.
Let me know if you if you would be interested in testing the
spreadsheet, or look out for it in the near future.
Thanks
Brian
Brian Tennant
Dept Clinical Biochemistry
Mayday Healthcare NHS Trust
020 8401 3548
-----Original Message-----
From: Clinical biochemistry discussion list
[mailto:[log in to unmask]] On Behalf Of David Burgess
Sent: 21 January 2010 14:32
To: [log in to unmask]
Subject: Xanthochromia Screening
Thanks for the quick answer to my question. There were 18 responses. 7
labs perform the analysis 24/7, some with consultant help for difficult
scans,
some with graphing program assists, some scan and report the following
morning.
8 labs provide a 9-5 service some at weekends as well, some would scan
and
report with consultant approval of request at any time, (this is what
happens
in our lab).
3 labs would scan and report all day and on the evening shift as well.
What a great resource!
David
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