Is it a common or rare syndrome? I wonder how one could recruit enough patients with this syndrome for any clinical trials or cohort or case control studies. If studies cannot be easily conducted due to an inadequate number of patients, it would be hard to retrieve literature you would need to write a systematic review. Just my two cents.
Misa
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-----Original Message-----
From: Evidence based health (EBH) [mailto:[log in to unmask]] On Behalf Of Olive Goddard
Sent: Friday, November 06, 2009 9:57 AM
To: [log in to unmask]
Subject: Re: levels of evidence for studies on pathophysiology
Dear Colleagues,
Can anyone respond to this query.
Have a good weekend everyone.
Olive
>>> Claudia Sommer <[log in to unmask]> 11/6/2009 2:45 pm >>>
Dear Ms Goddard,
my colleagues and I are trying to put together a systematic review on
the
pathophysiology of a certain syndrome. We have been looking for some
guidance on levels of evidence in studies on pathophysiology, but we
did not
find anything by that name. At present, we have adapted the Oxford
levels on
aetiology/diagnosis/symptom prevalence to our needs.
Has anybody, to your knowledge, previously used these or other levels
of
evidence for studies on pathophysiology, so that we could compare our
methods to those?
Thank you in advance for your help,
sincerely,
Claudia Sommer
--
Prof. Dr. Claudia Sommer
Neurologische Klinik
Universitätsklinikum Würzburg
Josef-Schneider-Str. 11
D-97080 Würzburg
Tel. +49 931 201 23763
Fax +49 931 201 23697
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http://www.klinik.uni-wuerzburg.de/neurologie
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