It's a vector containing the mean FA value for each subject.
Julie E. McEntee, M.A., C.C.R.P.
Senior Research Program Coordinator
Department of Psychiatry- Neuroimaging
Johns Hopkins University School of Medicine
600 N. Wolfe St./ Phipps 300
Baltimore, MD 21287
Phone: 410-502-0468
Fax: 410-614-3676
----- Original Message -----
From: "MCLAREN, Donald" <[log in to unmask]>
Date: Monday, January 5, 2009 11:50 am
Subject: Re: [SPM] fMRI 2nd-level analysis with covariates
To: Julie E McEntee <[log in to unmask]>
> Is the covariate of interest the FA value extracted from a region or
> the FA
> value at each voxel?
>
> On Mon, Jan 5, 2009 at 10:38 AM, Julie E McEntee <[log in to unmask]>
> wrote:
>
> > Hello SPMers,
> >
> > I am using the latest version/update of SPM5 with MatLab 7.0 on
> Windows XP
> > Professional 2002, service pack 3.
> >
> > I have 1st-level analyses (.con hdr/image files) consisting of the
> > difference between 2 task conditions for each of 2 groups (patients
> and
> > controls).
> >
> > There is a statistically significant difference between the 2
> groups in
> > years of education. I would like to include this as a "nuisance"
> variable at
> > 2nd-level analysis. I would also like to include a "covariate of interest"
> > (in this case fractional anisotrophy- FA). There is no correlation
> between
> > these 2 variables.
> >
> > What test should I use at the 2nd-level (and subsequent definition
> of
> > contrast weights) to answer the queston:
> >
> > Is FA related to the difference in BOLD response between groups?
> >
> > Thank-you for your help,
> >
> > Julie
> >
> > Julie E. McEntee, M.A., C.C.R.P.
> > Senior Research Program Coordinator
> > Department of Psychiatry- Neuroimaging
> > Johns Hopkins University School of Medicine
> > 600 N. Wolfe St./ Phipps 300
> > Baltimore, MD 21287
> > Phone: 410-502-0468
> > Fax: 410-614-3676
> >
>
>
>
> --
> Best Regards, Donald McLaren
> =====================
> D.G. McLaren
> University of Wisconsin - Madison
> Neuroscience Training Program
> Office: (608) 265-9672
> Lab: (608) 256-1901 ext 12914
> =====================
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