Yes Mohammad, in spite of my error in not appreciating
type 2 diabetes, this type of study is in many ways
similar to giving people antioxidants for disease
prevention and comparing them against a population who
have taken natural antioxidant containing foods all
their life. Therefore a following a healthy diet does
prevent diseases?
Regards
David Brown
--- Mohammad Al-Jubouri <[log in to unmask]> wrote:
> I would argue that at the age of 60, poorly
> cotrolled T2DM patients would have already had
> established atherosclerosis and therefore tightening
> glycaemic control is not going to reverse the
> process. Hence it is not surprising to find no
> benefit in major cardiovascular outcomes after tight
> glycaemic control in this cohort of patients.
> Treatment to targets for glycaemia (< 7%), lipid
> (LDL< 2.0) and BP (< 130/80) should be accomplished
> early in the course of T2DM, if we, at least, want
> to delay the occurrence of microvascular and
> macrovascular complications.
>
> regards
>
> Mohammad
> Dr. M A Al-Jubouri, MB ChB, MSc, FRCP Edin, FRCPath
> Consultant Chemical Pathologist
>
>
>
>
> ________________________________
> From: Kremmyda Angela <[log in to unmask]>
> To: [log in to unmask]
> Sent: Thursday, 22 January, 2009 9:48:58
> Subject: Re: Tight glycaemic control in type 2
> diabetes
>
> I can see your point but this is Type 2 diabetes
> we're talking about -
> how many children affected!? Which is probably why
> the mean age was 60.4
> years...
>
> Angela
>
> -----Original Message-----
> From: Clinical biochemistry discussion list
> [mailto:[log in to unmask]] On Behalf
> Of David Brown
> Sent: 22 January 2009 09:26
> To: [log in to unmask]
> Subject: Re: Tight glycaemic control in type 2
> diabetes
>
> Of course it is easy to read what you want to
> believe
> in one article.
> Perhaps we are looking at the wrong endpoint (HbA1c)
> and a case of too late to have any effect (mean age
> 60.4 years?).
> I defy anybody to convince us or the parents of a
> diabetic child that tight glusose control is not
> effective or not a good thing
> David Brown
>
>
> --- Jonathan Kay <[log in to unmask]>
> wrote:
>
>
>
>
>
>
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